TRANSFERABLE RESISTANCE AND AMINOGLYCOSIDE-MODIFYING ENZYMES IN ENTEROCOCCI
نویسندگان
چکیده
منابع مشابه
Transferable Resistance a N D in Enterococci Aminoglycoside-modifying Enzymes
Ten isolates of Streptococcus faecalis and two isolates of S. faecium were studied together with an NCTC strain of each species. Antibiotic susceptibility tests showed different patterns of high-level resistance to aminoglycosides. Three S. faecalis strains were highly resistant to gentamicin and other aminoglycosides. By means of a filter membrane technique, transfer of high-level resistance t...
متن کاملMolecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.
The three classes of enzymes which inactivate aminoglycosides and lead to bacterial resistance are reviewed. DNA hybridization studies have shown that different genes can encode aminoglycoside-modifying enzymes with identical resistance profiles. Comparisons of the amino acid sequences of 49 aminoglycoside-modifying enzymes have revealed new insights into the evolution and relatedness of these ...
متن کاملThe prevalence of aminoglycoside-modifying enzyme and virulence genes among enterococci with high-level aminoglycoside resistance in Inner Mongolia, China
This study highlights the prevalence of aminoglycoside-modifying enzyme genes and virulence determinants among clinical enterococci with high-level aminoglycoside resistance in Inner Mongolia, China. Screening for high-level aminoglycoside resistance against 117 enterococcal clinical isolates was performed using the agar-screening method. Out of the 117 enterococcal isolates, 46 were selected f...
متن کاملResistance Patterns and Prevalence of the Aminoglycoside Modifying Enzymes in Clinical Isolates of Gram Negative Pathogens
In this nationwide study we investigated the occurrence of aminoglycoside resistance patterns and prevalence of the aminoglycoside modifying enzymes (AMEs), aac(6), ant(2) and aph(3), in clinical isolates of Acinetobacter species, E. coli, Klebsiella species and Pseudomonas species isolates from various clinical specimens. A total of 319 clinical specimens recovered from urine, blood, wound, ca...
متن کاملResistance due to aminoglycoside modifying enzymes in Pseudomonas aeruginosa isolates from burns patients.
BACKGROUND & OBJECTIVE Enzymatic modifications of aminoglycosides result in high-level resistance in numerous bacterial species. However, the data on this aspect are elementary in our country. The present study was therefore designed to determine resistance rates and patterns, and to find out the prevalent aminoglycoside modifying enzymes (AMEs) in clinical isolates of Pseudomonas aeruginosa fr...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1985
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-20-2-187